Curcumin, Depression and Other Brain Disorders

Curcumin’s value in treating dementia and Alzheimer’s disease opens the door to its considerable value in treating and preventing a variety of other malfunctions of the brain and the neurotransmitter system.

DEPRESSION  Image result for depression images curcumin

Over a lifetime, 16.5% of the U.S. adult population (18.8 million people) suffers from a major depressive disorder and 30% of those cases are so severe that they impair the ability to work or even to function in the world in the normal terms. We know that women are 70% more likely  to develop depression, that Caucasian have a 40% higher risk for depression, than African-Americans and that people between the ages of 18 and 29 are at a much greater risk of major depression disorders than people over 60.

Depression affects children as well. Government statistics show 4.7% of 13 to 18- year olds suffer from severe mood disorders and girls are nearly twice as vulnerable as boys. The rate of teen depression is increasing by an alarming 23% per year.

We’re not talking about the  occasional day or even days of feeling blue. We’re not talking about the normal ups and downs of life, the loss of a relationship, the loss of a job or even loss of a loved one.

Depressive disorder  is a crushing inability to cope with life and the world. Yet only about half of its sufferers get treatment and 80%  of the treatment that conventional medicine offers is completely ineffective. 

Standard medical treatment for depression  is usually a series of antidepressant pharmaceuticals with a high risk of serious side effects and little or no effect.  Research shows that antidepressants work for only 35 to 45% of the population, and some figures suggest the effectiveness rate is as low as 30%. Worse yet, antidepressants like Prozac, Paxil and Zoloft have been linked to suicide, violence, psychosis, abnormal bleeding and brain tumors.

What causes depression? Certainly short term depression can be the result of life events. Long-term trauma, such as sexual abuse and family history of depression can also be factors.

Dr. Hyla Cass, a cutting edge integrative physician with a specialty in psychiatry, believes that the cause of depression is often biochemical, an imbalance in brain chemistry.

The answer, says Dr. Cass in her book Natural Highs: Feel Good All The Time, is in”a variety of nutrients that both make up and fuel the brain, nervous system and neurotransmitters. So a low mood may have less to do with past trauma or a faulty belief system than with deficient nutrients.”

“Mood-lifting serotonin, motivating noradrenaline and sleep-enhancing tryptophan are the neurotransmitters most often deficient in people with depression.” says Dr. Cass.

 You guess it: Here comes the Golden Knight on his charger again, offering solutions to brain imbalances that are at the foundation of major depression. Not only does Curcumin enhance noradrenaline and tryptophan levels, but it also increases the production of dopamine, another neurotransmitter that controls emotional response and the ability to experience pleasure and pain.

Numerous studies underscore Curcumin’s ability to improve levels of neurotransmitters and thereby improve mood.

Many people stumble on Curcumin’s antidepressant action when take it for another condition, most typically to address joint pain.  The action is so subtle that some users have written that they didn’t realize their depression had disappeared until they stopped taking Curcumin and the depression returned.  Here are highlights of the research on Curcumin and depression:

 Image result for seratonin

Increases serotonin and dopamine levels:  Several studies supports Curcumins’s ability to boost mood by increasing levels of mood-enhancing neurotransmitters. At least one study adds that Curcumin combined with some antidepressant prescription drugs improves their effectiveness.

 Acts like pharmaceutical drugs without the risks: Exciting new research shows that BCM-95 Curcumin is as effective as the popular antidepressant pharmaceuticals Prozac (fluoxetine) and Tofranil (imipramine),  without the side effects associated with the pharmaceutical drugs that include weight gain and loss, increased depression and increased suicidal tendencies. Another interesting finding  published in 2011 showed that BCM-95 Curcumin did nothing to increase the effectiveness of the two pharmaceutical antidepressants, but did just as well as each of them on its own. The bottom line:   If you suffer from depression, it is well worth a try to go with BCM-95 Curcumin, with the permission of your health care professional. Please don’t stop taking your antidepressants cold turkey because it can cause some serious side effects like   dramatic mood swings, a worsening of the under lying depression or other conditions, extremely vivid dreams, aggression and suicidal tendencies.

 Generates new brain cells:  Curcumin can actually help in the formation of new nerve cells, called neurogenesis, helping create a healthy balance of the numerous neurotranmitters needed for a healthy brain, better memory and a positive mood. Image result for neurogenesis

Antioxidant and anti-inflammatory mood improvement: Indian researchers are clearly enthusiastic about Curcumin.  Several studies  further the body of evidence in favor of Curcumin’s positive effects on mood.


Curcumin’s ability to relieve depression and dementia are considerable, but there’s more in the realm of scientific research on Curcumin’s brain-protective effects:

 Blocks brain tumor formation:  Researchers in New York discovered that injected Curcumin blocks the formation of Cancerous Brain Tumors in mice.  

Anti-convulsant: An animal study from India found that Curcumin supplement stop epileptic seizures.

 Protects brain cells from stroke damage: Oxygen deprivation is the main cause of post-stroke brain damage and disability. A University of   Missouri animal study showed that injection Curcumin given for two months after a stroke greatly diminished the death of brain cells. Another study showed that after a stroke, Curcumin helped prevent damage to the all-important blood brain barrier, minimizing the risk of infection and other types of brain damage.

Counters effects of traumactic brain injury:  UCLA  researchers found that a diet high in Curcumin greatly reduced brain damage and cognitive impairment after a traumatic brain injury.

 Treatment for Parkinson’s disease: Parkinson’s disease is a degenerative disease of the central nervous system that includes movement-related impairment, including shaking, slowness of movement and rigidity of limbs. In its advanced state,  Parkinson’s can include dementia and behavioral problems.

 Modern medicine treats the symptoms of Parkinson’s  since there is no known cure.  

Inflammation is certainly a part of Parkinson’s , and we already know that Curcumin is a powerful anti-inflammatory and anti-oxidant. In addition, 2012 research from Northeast Ohio Medical University suggest that Curcumin has neuroprotective elements as well, particularly  in containing the protein accumulations like the plaques and tangles found in Alzheimer’s. Researchers in that study said, “Curcumin possesses therapeutic potential in the amelioration of a host of neurodegenerative ailments as evidenced by its antioxidant, anti-inflammatory and anti-protein aggregation effects”

Who knows what the future holds, but this research may eventually show Curcumin’s value in treating other neurodegenerative diseases like multiple sclerosis and ALS. In another study, Indian researchers concluded that Curcumin holds therapeutic potential for people with Parkinson’s disease because of its antioxidant properties, especially those that help rebuild glutathione levels in cells, enhancing nutrient metabolism and immune response.  

Image result for BCM 95

And she concludes if you or your love one suffer from depression, or other Brain disorder run don’t walk to your nearest health food store and get some BCM-95 Curcumin, you have nothing to risk and everything to gain. Next take this and your prescription to your doctor and ask how to wean your self off of the drugs and start taking BCM-95. Please don’t forget to ask your doctor first. My first day of taking BCM-95 my blood pressure drop so low I had to stop taking my BP medicine. This is real, it really works . This is all from a book by Dr. Jan McBarron.



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