This is from another source, a man named Clayton Geoffreys. My mission this month or so , is to find as much as I can on Curcumin. I am so excited about Curcumin that I want to find out as much as I can from all different sources. And I am still taking Curcumin, for everything that is wrong with me and so I don’t get Alzheimer’s.
How is Curcumin Absorbed ?
The most major drawback with Curcumin is its bioavailability within the human body; it has insufficient solubility. It has lower absorption from the intestines, rapid metabolism, and rapid elimination. The lymph system absorbs it; then it is rapidly eliminated.
This is probably why the remarkable properties that Curcumin possesses have been widely overlooked.
However, the discovery of black pepper in combination with Curcumin has made a big difference. Black pepper is a spice native to India as well. The chemical piperine is used for relief from respiratory condition, the common cold, dental disease, heart disease, muscular strains, and indigestion. It has antibacterial properties and is used to preserve food. It is a source of potassium, iron, vitamin C vitamin K, and manganese. Clearly, there is no surprise that black pepper and Curcumin, or Turmeric, make a great pair. Given that both spices are found in the same indigenous area of India, it is likely that the native population has been mixing the two together for centuries. It is possible, that this has been the reason, they have not been as susceptible to disease as the rest of us.
Research has been coming up with new nanotechnology that is making improvements on the bioavailability of Curcumin, which makes it more soluble in water, something to look out for.
How Much Curcumin Do We Need ?
Topically applied, Curcumin is absorbed efficiently through the skin. It has a favorable effect on healing wounds, fungal infections bacterial infections, skin cancer, and inflammation of targeted organs. It is also useful as a photosensitizer, which means that it works with the aid of light without harming host tissue.
Curcumin has had some positive results in absorption through nasal delivery, which increases nose to brain drug transport. Pharmacokinetic results show the absolute bioavailability of Curcumin through intranasal administration. The distribution of Curcumin in the brain was higher than intravenous administration. This helps increase drug targeting efficiencies of Curcumin in the cerebrum, cerebellum, hippocampus, and olfactory bulb portions of the brain due to increased distribution and bioavailbility of Curcumin in tissue. Curcumin has also been administered as an intravenous drug with very positive results in many research studies.
Still, with all this, to receive full benefits of Curcumin, one must take it in supplement form. The most typically bioavailable form is Curcumin in an encapsulated, supplemental form that should be 500mg 95% standardized, with black pepper extract, or its agent, piperine. For most malasdies, it should be taken once a day. For more severe conditions such as pain from arthritis, it is safe to increase Curcumin dosage until relief has been reached. In laboratory studies, up to 8 grams have been taken daily without any negative side effects, except when used with a few blood thinning medications. In any event, the chances are that you will not need a dosage that high. The real trick is making Curcumin more bioavailable for the human body. Advances have been made to make curcumin is much more efficient, and Curcumin analogs are being researched to make it more available to the general public.